Potassium Cation → 5-[4-(1,1-Dioxidothiomorpholin-4-yl)phenyl]-2-({6-[(2-hydroxy-2-methylpropoxy)methyl]pyridin-2-yl}amino)thiophene-3-carboxamide
Reaction equation
[Br:28][c:29]1[cH:30][cH:31][cH:32][c:33]([CH2:35][O:36][CH2:37][C:38]([CH3:39])([OH:40])[CH3:41])[n:34]1.[CH3:48][OH:49].[K+:42].[K+:43].[N:26]#[N:27].[O-:44][C:45]([O-:46])=[O:47].[O:1]=[S:2]1(=[O:25])[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][c:11](-[c:14]3[cH:15][c:16]([C:22](=[O:23])[NH2:24])[c:17]([N+:19]([O-:20])=[O:21])[s:18]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1.[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[O:88]=[C:89]([CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1)[CH:98]=[CH:99][c:100]1[cH:101][cH:102][cH:103][cH:104][cH:105]1.[Pd:50].[Pd:51]>>[O:1]=[S:2]1(=[O:25])[CH2:3][CH2:4][N:5]([c:8]2[cH:9][cH:10][c:11](-[c:14]3[cH:15][c:16]([C:22](=[O:23])[NH2:24])[c:17]([NH:19][c:29]4[cH:30][cH:31][cH:32][c:33]([CH2:35][O:36][CH2:37][C:38]([CH3:39])([OH:40])[CH3:41])[n:34]4)[s:18]3)[cH:12][cH:13]2)[CH2:6][CH2:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-55034f8b17d64448857c7e06363c93f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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