Dimethylformamide → tert-Butyl 4-((trimethylsilyl)oxy)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 101252Notes

Reaction equation

HRID 101252 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:15][Si:16]([CH3:17])([CH3:18])[Cl:19].[CH3:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]=[C:11]([O:14][Si:16]([CH3:15])([CH3:17])[CH3:18])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6397ChlorotrimethylsilaneHCID 8058HexaneHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 10778540tert-Butyl 4-((trimethylsilyl)oxy)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-b7090b247ea643a98eef3c1175cf2759
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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