HCID 67207170, compound → HCID 67205268, compound

HRID 1013399Notes

Reaction equation

HRID 1013399 reaction equation
C([O:3][C:4]([CH:6]1[CH:11]([C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)[CH2:10][CH2:9][N:8]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:7]1)=[O:5])C>Cl>[CH2:17]([N:8]1[CH2:9][CH2:10][CH:11]([C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)[CH:6]([C:4]([OH:5])=[O:3])[CH2:7]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 1

HCID 67207170HCID 67207170, compound

Product 1

HCID 67205268HCID 67205268, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

The product from step b) (6.83 g, 20.7 mmol) was treated with 4 M HCl (400 ml) at 100° C. for 16 hours. Next, the reaction was evaporated to dryness, azeotroped with toluene (2×50 ml) and placed on the high vacuum to give the subtitle compound (7 g, 100%). MS calculated for C17H19NO2S−H 300, observed 300.

Workup

  1. customNext, the reaction was evaporated to dryness
  2. customazeotroped with toluene (2×50 ml)

Sources & evidence

ORD record
ord-70bb625d14124f23bc2e0d1ee4f0bf56
Source dataset
uspto-grants-2011_07
Patent number
US07981919B2

Reaction notes

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