HRID1013436

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC

HCID107807

Perindopril

C19H32N2O5

结构：O=C(O)CCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1

HCID57626172

未命名化合物

PRODUCTS

生成物

结构：CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC.O=C(O)CCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1

HCID67318167

未命名化合物

PROCEDURE

实验过程

The compound is obtained according to the procedure described in Step E of Example 1, starting from perindopril and the compound obtained in Step B of Example 1.

WORKUP

后处理

customThe compound is obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fa3e6970647b47f08448aa92d73e679b
来源数据集: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07981920B2
来源说明: uspto-grants-2011_07

反应 SMILES

[CH3:1][CH2:2][CH2:3][C@H:4]([NH:10][C@H:11]([C:13]([N:15]1[C@H:23]([C:24]([OH:26])=[O:25])[CH2:22][C@H:21]2[C@@H:16]1[CH2:17][CH2:18][CH2:19][CH2:20]2)=[O:14])[CH3:12])[C:5]([O:7][CH2:8][CH3:9])=[O:6].[O-:27][N+:28]1[O:32][N:31]=[C:30]([O:33][CH2:34][CH2:35][C:36]([OH:38])=[O:37])[C:29]=1[S:39]([C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1)(=[O:41])=[O:40]>>[O-:27][N+:28]1[O:32][N:31]=[C:30]([O:33][CH2:34][CH2:35][C:36]([OH:38])=[O:37])[C:29]=1[S:39]([C:42]1[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=1)(=[O:40])=[O:41].[CH2:8]([O:7][C:5]([C@@H:4]([NH:10][C@@H:11]([CH3:12])[C:13]([N:15]1[C@@H:16]2[C@@H:21]([CH2:20][CH2:19][CH2:18][CH2:17]2)[CH2:22][C@H:23]1[C:24]([OH:26])=[O:25])=[O:14])[CH2:3][CH2:2][CH3:1])=[O:6])[CH3:9]