Perindopril → 3-[(5-Oxido-4-(phenylsulphonyl)-1,2,5-oxadiazol-3-yl)-oxy]-propionic Acid (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-butyl]-amino}-propionyl]-octahydro-1H-indole-2-carboxylic Acid

Participants

Role	Name	HCID	Charge
Reactant	Perindopril	HCID 107807	—
Reactant	3-[[4-(Benzenesulfonyl)-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]oxy]propanoic acid	HCID 57626172	—
Product	3-[(5-Oxido-4-(phenylsulphonyl)-1,2,5-oxadiazol-3-yl)-oxy]-propionic Acid (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-butyl]-amino}-propionyl]-octahydro-1H-indole-2-carboxylic Acid	HCID 67318167	—

Reaction Steps

The compound is obtained according to the procedure described in Step E of Example 1, starting from perindopril and the compound obtained in Step B of Example 1.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07981920B2
Source dataset	uspto-grants-2011_07
ORD ID	ord-fa3e6970647b47f08448aa92d73e679b
Source note	uspto-grants-2011_07