Hydrochloric Acid → HCID 57925887, compound

Participants

Reaction Steps

[4-(tert-Butoxycarbonyl)phenyl]methylphosphinic acid]. tert-Butyl 4-[ethoxy(methyl) phosphoryl]benzoate (510 mg, 1.79 mmol) was made 0.25 M in dioxane and to this stirring solution was added potassium hydroxide (5.38 mL, 5.38 mmol). The resulting mixture was stirred at ambient temperature for 10 minutes. The reaction mixture was neutralized with 1 eq aq HCl then concentrated in vacuo. The residue was diluted with MeOH, the inorganic salts were filtered off and the filtrate was concentrated in vacuo. MS: cal'd 257 (MH+), exp 257 (MH+).

Provenance & Evidence