Hydrochloric Acid → HCID 57925897, compound

Participants

Reaction Steps

4-[1-(Dimethoxy-phosphoryl)-1-fluoro-ethyl]-benzoic acid methyl ester (0.56 g, 1.93 mmol) was made 0.25 M in dioxane and to this stirring solution was added 3 M aqueous LiOH (0.14 g, 5.79 mmol). The resulting mixture was stirred at ambient temperature for 18 hours. The mixture was neutralized with 1N aq HCl and concentrated in vacuo. The residue was carried forward without further purification: MS: cal'd 277 (MH+), exp 277 (MH+)

Provenance & Evidence