HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → (4-Acetoxy-3-ethoxyphenyl)-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetoxy-(4-acetoxy-3-ethoxyphenyl)-acetic acid | HCID 20778781 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (4-Acetoxy-3-ethoxyphenyl)-acetic acid | HCID 20778780 | 88.8% |
Reaction Steps
Intermediate 3 (30.9 g, 0.104 mol) was dissolved in methanol (500 mL), Pd(OH)2 (5.0 g) wet with distilled water was added, and the mixture was placed under hydrogen at 30 psi with shaking. After 48 hr Pd(OH)2 was removed by filtration and solvent was removed under vacuum giving 22 g of intermediate 4 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07981931B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-a325931a25874d43927f9d58273b244c |
| Source note | uspto-grants-2011_07 |