2-Imidazolidinone → HCID 66877610, compound

HRID 1014021Notes

Reaction equation

Br[C:2]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][C:3]=1[C:4]#[N:5].[NH:11]1[CH2:15][CH2:14][NH:13][C:12]1=[O:16]>>[ClH:10].[NH2:5][CH2:4][C:3]1[CH:6]=[C:7]([Cl:10])[CH:8]=[CH:9][C:2]=1[N:11]1[CH2:15][CH2:14][NH:13][C:12]1=[O:16]

Participants

Reactant 2

HCID 84532-Imidazolidinone

HCID 103309442-Bromo-5-chlorobenzonitrile

Product 1

HCID 66877610HCID 66877610, compound

Procedure

(Step 1) Using 2-bromo-5-chlorobenzonitrile and imidazolidin-2-one, and in the same manner as in the Example 35, Steps 1 to 3, 1-[2-(aminomethyl)-4-chlorophenyl]imidazolidin-2-one hydrochloride was obtained.

Sources & evidence

ORD record: ord-1687c334f34a4352b7201f9f964add99
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07982044B2

Reaction notes

Loading…