Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1014065Generated: October 30, 2026

N-Hydroxyacetamidine → HCID 11286666, compound

https://huagongshe.com/reaction/1014065

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-HydroxyacetamidineHCID 30926—
Reactant3-Cyclopropyl-3-Oxopropionic Acid Methyl EsterHCID 10130016—
SolventTolueneHCID 1140—
ProductHCID 11286666HCID 11286666—

Reaction Conditions

Temperature130 °C

Reaction Steps

Under an inert atmosphere, acetamidoxime (1.56 g) is added to a solution of methyl 3-cyclopropyl-3-oxopropanoate (3.0 g) in 50 ml of toluene; the stirred mixture is heated to 130° C. while distilling off the solvent and methanol formed in the reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07982047B2
Source datasetuspto-grants-2011_07
ORD IDord-b1f25107b023422998b604f5eeb55687
Source noteuspto-grants-2011_07