Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1,3-Propanedione, 1-[2-chloro-4-(methylsulfonyl)phenyl]-3-cyclopropyl- | HCID 11012052 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11314987 | HCID 11314987 | — |
Reaction Steps
Under an inert atmosphere, bromine (0.24 g) is slowly added dropwise to a solution of (1-[2-chloro-4-(methylsulphonyl)phenyl]-3-(cyclopropyl)propan-1,3-dione (0.43 g) in 25 ml of dichloromethane cooled to 5° C., then the mixture is stirred overnight at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07982047B2 |
|---|
| Source dataset | uspto-grants-2011_07 |
|---|
| ORD ID | ord-5dda7d2c536f411bb25fa53385e98490 |
|---|
| Source note | uspto-grants-2011_07 |
|---|
