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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1015032Generated: October 31, 2026

Phosphorus oxide (P4O10) → 1-Methyl-3,4-dihydroisoquinoline

https://huagongshe.com/reaction/1015032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxide (P4O10)HCID 14812—
ReactantN-(2-phenylethyl)acetamideHCID 70143—
Product1-Methyl-3,4-dihydroisoquinolineHCID 231502—

Reaction Steps

In close analogy to the procedure described above, N-phenethyl-acetamide is reacted with phosphorus pentoxide to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07985753B2
Source datasetuspto-grants-2011_07
ORD IDord-0b1146578704439490c07767eb4748c9
Source noteuspto-grants-2011_07