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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1015040Generated: October 27, 2026

Phosphorus oxide (P4O10) → 5-Methoxy-1-methyl-3,4-dihydroisoquinoline

https://huagongshe.com/reaction/1015040

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxide (P4O10)HCID 14812—
ReactantN-[2-(2-methoxyphenyl)ethyl]acetamideHCID 4053755—
Product5-Methoxy-1-methyl-3,4-dihydroisoquinolineHCID 45091195—

Reaction Steps

In close analogy to the procedure described above, N-[2-(2-methoxy-phenyl)-ethyl]-acetamide is reacted with phosphorus pentoxide to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07985753B2
Source datasetuspto-grants-2011_07
ORD IDord-960451b4c21e46e08e30f2549d789984
Source noteuspto-grants-2011_07