Sodium triacetoxyborohydride → HCID 18613788, compound

HRID 1015050Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][N:8]=[C:9]2[CH3:12])=[CH:4][CH:3]=1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH2:6][CH2:7][NH:8][CH:9]2[CH3:12])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 5049666Sodium triacetoxyborohydride

HCID 110952137-Chloro-3,4-dihydro-1-methylisoquinoline

Product 1

HCID 18613788HCID 18613788, compound

Procedure

In close analogy to the procedure described above, 7-chloro-1-methyl-3,4-dihydro-isoquinoline is reacted with sodium triacetoxyborohydride to provide the title compound.

Sources & evidence

ORD record: ord-d1caee6466ee44899a9887ed3e588b1a
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07985753B2

Reaction notes

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