Sodium triacetoxyborohydride → HCID 18613754, compound

HRID 1015053Notes

Reaction equation

[F:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]=[C:7]2[CH3:12].C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[F:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][NH:6][CH:7]2[CH3:12]

Participants

Reactant 2

HCID 5049666Sodium triacetoxyborohydride

HCID 58416485HCID 58416485, compound

Product 1

HCID 18613754HCID 18613754, compound

Procedure

In close analogy to the procedure described above, 5-fluoro-1-methyl-3,4-dihydro-isoquinoline is reacted with sodium triacetoxyborohydride to provide the title compound.

Sources & evidence

ORD record: ord-1a6c19167c0445948db09ddc60a14276
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07985753B2

Reaction notes

Loading…