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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1015076Generated: October 30, 2026

Boronic Acid → 1-Methyl-5-pyridin-3-yl-1,2,3,4-tetrahydro-isoquinoline

https://huagongshe.com/reaction/1015076

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant5-Bromo-1,2,3,4-tetrahydro-1-methylisoquinolineHCID 59662594—
Product1-Methyl-5-pyridin-3-yl-1,2,3,4-tetrahydro-isoquinolineHCID 58416375—

Reaction Steps

In close analogy to the procedure described above, 5-Bromo-1-methyl-1,2,3,4-tetrahydro-isoquinoline is reacted with the corresponding boronic acid to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07985753B2
Source datasetuspto-grants-2011_07
ORD IDord-6b46537555824dcf98ccdc6682dda24b
Source noteuspto-grants-2011_07