HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluorobenzonitrile → HCID 67301356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluorobenzonitrile | HCID 74695 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | HCID 67301499 | HCID 67301499 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67301356 | HCID 67301356 | 100% |
Reaction Steps
4-(2-Chlorobenzyl)cyclohexylmethanol (68 mg; 0.28 mmol) and 2,6-difluorobenzonitrile (40 mg; 0.28 mmol) were carried out using Method I with potassium t-butoxide (35 mg; 0.31 mmol) in 1.5 mL of dimethylformamide. Material was purified by flash chromatography to give 100 mgs of title compound as a colorless oil. (100% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07985755B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-b317d9d8f7a5405198a03d1f71792ea0 |
| Source note | uspto-grants-2011_07 |