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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1015917Generated: November 2, 2026

Hydrochloric Acid → 4-(2-Chloroethyl)phenol

https://huagongshe.com/reaction/1015917

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTyrosolHCID 10393—
Product4-(2-Chloroethyl)phenolHCID 316721—

Reaction Steps

In a similar process using 12N HCl, 2-(4-hydroxyphenyl) ethanol gave 70% isolated yield of the (2-[4-hydroxyphenyl]ethyl) chloride. 1H NMR (CDCl3) δ 2.96 (2H, t, J=7.8 Hz), 3.67 (2H, t, J=7.2 Hz), 6.79 (2H, d, J=8.4 Hz), 6.94 (2H, d, J=8.1 Hz)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07985879B2
Source datasetuspto-grants-2011_07
ORD IDord-861e1c8f4a5346bbbe38c46fe27d4e90
Source noteuspto-grants-2011_07