反应详情

A mixture of the nitro compound, 3-[(trimethylsilyl)ethynyl]nitrobenzene, prepared as described above (0.86 g, 3.92 mmol) in 2-propanol (30 mL) was degassed with nitrogen and treated with 5% platinum on alumina (268 mgs). The mixture was shaken under an atmosphere of hydrogen (30 psi) on a Parr shaker apparatus for 22 hours. The reaction mixture was filtered through a short pad of Celite™ (diatamaceous earth) and concentrated by evaporation to give an oil which was dried in vacuo overnight to give the title product (692 mg, 93%) as a yellow brown oil.

1. customprepared
2. customwas degassed with nitrogen
3. additiontreated with 5% platinum on alumina (268 mgs)
4. filtrationThe reaction mixture was filtered through a short pad of Celite™ (diatamaceous earth)
5. concentrationconcentrated by evaporation
6. customto give an oil which
7. customwas dried in vacuo overnight