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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1016842Generated: October 31, 2026

2-Thiopheneacetic acid → 2-[(2-Thienyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/1016842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetic acidHCID 15970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Thienyl)acetamido]butyric acid isobutyl esterHCID 54443682—

Reaction Steps

Following General Procedure I′ above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06476263B1
Source datasetuspto-grants-2002_11
ORD IDord-22534fc149fe41b3bd755cf040a6d843
Source noteuspto-grants-2002_11