Water → HCID 18403024, compound

HRID 1017132Notes

Reaction equation

HRID 1017132 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].O.[OH-].[Na+].[C:14](#[N:17])[CH:15]=[CH2:16]>C(O)(=O)C>[C:14]([CH2:15][CH2:16][NH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6])#[N:17]

Participants

6

Reactant 4

HCID 962WaterHCID 74193-Aminobenzoic AcidHCID 7855AcrylonitrileHCID 14798Sodium Hydroxide

Product 1

HCID 18403024HCID 18403024, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
5 °C

Procedure

200.0 g of 3-aminobenzoic acid in 2 1 of water were admixed with 53.2 g of sodium hydroxide. At 30° C., 126.6 g of acrylonitrile were added dropwise, and the mixture was then heated under reflux for 22 hours. The mixture was then cooled to 5° C. and acetic acid was added (pH=5) and the precipitate which had formed was filtered off with suction and washed with water.

Workup

  1. temperaturethe mixture was then heated
  2. temperatureunder reflux for 22 hours
  3. customthe precipitate which had formed
  4. filtrationwas filtered off with suction
  5. washwashed with water

Sources & evidence

ORD record
ord-1f4ae3be3b064e63b7e49a8bcf3d55be
Source dataset
uspto-grants-2002_11
Patent number
US06479436B1

Reaction notes

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