HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Phenol, 5-chloro-2-methoxy-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 5-Chloro-2-methoxyphenylboronic acid | HCID 2735751 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Hydrogen Peroxide | HCID 784 | — |
| Product | Phenol, 5-chloro-2-methoxy- | HCID 588774 | — |
Reaction Steps
A solution of 5-chloro-2-methoxy benzeneboronic acid (1.9 g, 10 mmol) in hydrogen peroxide (2.04 ml, 30% solution) and ethanol 40 ml was refluxed for 30 min. Water was added and the product was extracted with two portions of ethyiacetate. Drying over magnesium sulfate and evaporation of the solvent gave the product as an oil. Yield 1.05 g, 65%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479491B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-318d396a9e96424597274760a712396d |
| Source note | uspto-grants-2002_11 |