3-Methoxypropylamine → HCID 18002051, compound

HRID 1017309Notes

Reaction equation

HRID 1017309 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[CH3:17][O:18][CH2:19][CH2:20][CH2:21][NH2:22]>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:22][CH2:21][CH2:20][CH2:19][O:18][CH3:17])[N:3]=1

Participants

4

Reactant 2

HCID 16723-MethoxypropylamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 18002051HCID 18002051, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-(3-methoxypropylamino)-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 3-methoxypropylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-0c53db787447455c80dd44618cf7fb26
Source dataset
uspto-grants-2002_11
Patent number
US06479487B1

Reaction notes

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