4-Piperidone → 1-[(4-Methoxyphenyl)methyl]-4-piperidinone

HRID 1017327Notes

Reaction equation

HRID 1017327 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.[CH3:8][O:9][C:10]1[CH:17]=[CH:16][C:13]([CH2:14]Cl)=[CH:12][CH:11]=1>>[CH3:8][O:9][C:10]1[CH:17]=[CH:16][C:13]([CH2:14][N:1]2[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]2)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 337214-PiperidoneHCID 699934-Methyloxybenzyl chloride

Product 1

HCID 119595801-[(4-Methoxyphenyl)methyl]-4-piperidinone

Procedure

1-(4-Methoxybenzyl)-4-piperidone is prepared from 4-piperidone and 4-methoxybenzyl chloride essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record
ord-296ff7baf8304acdb9b88897e731ccc7
Source dataset
uspto-grants-2002_11
Patent number
US06479487B1

Reaction notes

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