m,alpha-Dichlorotoluene → HCID 10489300, compound
Reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.[Cl:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12]Cl>>[Cl:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1Participants
3
Procedure
1-(3-Chlorobenzyl)-4-piperidone is prepared from 4-piperidone and 3-chlorobenzyl chloride essentially as described above in Example 38, Scheme C, step a.
Sources & evidence
- ORD record
- ord-907fb7bd73b946f998252608f751d6c7
- Source dataset
- uspto-grants-2002_11
- Patent number
- US06479487B1
Reaction notes
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