4-Piperidone → 1-(3-Phenoxypropyl)piperidin-4-one

HRID 1017339Notes

Reaction equation

HRID 1017339 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[O:12]([CH2:11][CH2:10][CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 337214-PiperidoneHCID 76917(3-Chloropropoxy)benzene

Product 1

HCID 180022221-(3-Phenoxypropyl)piperidin-4-one

Procedure

1-(3-Phenoxypropyl)-4-piperidone is prepared from 4-piperidone and 1-chloro-3-phenoxypropane essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record
ord-5c7583083cdf4d398782961b29e7841e
Source dataset
uspto-grants-2002_11
Patent number
US06479487B1

Reaction notes

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