Benzene, (2-chloroethoxy)- → 1-(2-Phenoxyethyl)-4-piperidone

HRID 1017341Notes

Reaction equation

HRID 1017341 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[O:11]([CH2:10][CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 12156Benzene, (2-chloroethoxy)-HCID 337214-Piperidone

Product 1

HCID 180020361-(2-Phenoxyethyl)-4-piperidone

Procedure

1-(2-Phenoxyethyl)-4-piperidone is prepared from 4-piperidone and 1-chloro-2-phenoxyethane essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record
ord-ca10843218574b70b8b30eb4c7bd669c
Source dataset
uspto-grants-2002_11
Patent number
US06479487B1

Reaction notes

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