4-Piperidone → N-Phenethyl-4-piperidinone

HRID 1017343Notes

Reaction equation

HRID 1017343 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[C:11]1([CH2:10][CH2:9][N:1]2[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 337214-PiperidoneHCID 2314961-Chloro-2-phenylethane

Product 1

HCID 96437N-Phenethyl-4-piperidinone

Procedure

1-(2-phenylethyl)-4-piperidone is prepared from 4-piperidone and (2-chloroethyl)benzene essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record
ord-33699b9d499c468f859a4afc2547101b
Source dataset
uspto-grants-2002_11
Patent number
US06479487B1

Reaction notes

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