N-Phenethyl-4-piperidinone → 1-(2-Phenylethyl)-4-piperidone oxime

HRID 1017344Notes

Reaction equation

[C:1]1([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][C:12](=O)[CH2:11][CH2:10]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:17][OH:18]>>[C:1]1([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][C:12](=[N:17][OH:18])[CH2:11][CH2:10]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 96437N-Phenethyl-4-piperidinone

HCID 443297Hydroxyamine hydrochloride

Product 1

HCID 143303451-(2-Phenylethyl)-4-piperidone oxime

Procedure

1-(2-Phenylethyl)-4-piperidone oxime is prepared from 1-(2-phenylethyl)-4-piperidone and hydroxylamine hydrochloride essentially as described above in Example 38, Scheme C, step b.

Sources & evidence

ORD record: ord-b3e4b3fca4e54c1e9fa097b4726b63de
Source dataset: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06479487B1

Reaction notes

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