4-Piperidone → 1-(3-Methoxypropyl)-4-piperidinone

HRID 1017360Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][CH2:11][O:12][CH3:13]>>[CH3:13][O:12][CH2:11][CH2:10][CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 337214-Piperidone

HCID 1189271-Chloro-3-methoxypropane

Product 1

HCID 180020081-(3-Methoxypropyl)-4-piperidinone

Procedure

1-(3-Methoxypropyl)-4-piperidone is prepared from 4-piperidone and 1-chloro-3-methoxypropane essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record: ord-00542969d3ae4d6484f740ed5f181a07
Source dataset: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06479487B1

Reaction notes

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