Hydroxyamine hydrochloride → 1-(3-Benzyloxypropyl)-4-piperidone oxime

HRID 1017369Notes

Reaction equation

HRID 1017369 reaction equation
[CH2:1]([O:8][CH2:9][CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][C:15](=O)[CH2:14][CH2:13]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:20][OH:21]>>[CH2:1]([O:8][CH2:9][CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][C:15](=[N:20][OH:21])[CH2:14][CH2:13]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 180019321-(3-Benzyloxypropyl)-4-piperidone

Product 1

HCID 180018001-(3-Benzyloxypropyl)-4-piperidone oxime

Procedure

1-(3-Benzyloxypropyl)-4-piperidone oxime is prepared from 1-(3-benzyloxypropyl)-4-piperidone and hydroxylamine hydrochloride essentially as described above in Example 38, Scheme C, step b.

Sources & evidence

ORD record
ord-9b09a8bf79344bcc97da249050622a65
Source dataset
uspto-grants-2002_11
Patent number
US06479487B1

Reaction notes

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