4-Piperidone → 1-(6-Benzyloxyhexyl)-4-piperidone
Reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1Participants
3
Procedure
1-(6-Benzyloxyhexyl)-4-piperidone is prepared from 4-piperidone and 1-chloro-6-benzyloxyhexane essentially as described above in Example 38, Scheme C, step a.
Sources & evidence
- ORD record
- ord-d79d1037654e41f89e2aa98e3983023a
- Source dataset
- uspto-grants-2002_11
- Patent number
- US06479487B1
Reaction notes
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