4-Piperidone → 41661-54-5
Reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][C:10]1[S:11][CH:12]=[CH:13][CH:14]=1>>[S:11]1[CH:12]=[CH:13][CH:14]=[C:10]1[CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1Participants
3
Procedure
1-(2-Thiopheneyl)methyl-4-piperidone is prepared from 4-piperidone and 2-(chloromethyl)thiophene essentially as described above in Example 38, Scheme C, step a.
Sources & evidence
- ORD record
- ord-8fef704afeb14bc6bd8244b98e371129
- Source dataset
- uspto-grants-2002_11
- Patent number
- US06479487B1
Reaction notes
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