3-(3-Benzyl-3h-imidazol-4-yl)-1-(4-isobutylphenyl)-propen-1-one → 3-(3-Benzyl-3H-imidazol-4-yl)-5-isobutylindan-1-one

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 3-(3-benzyl-3H-imidazol-4-yl)-1-(4-isobutylphenyl)-propen-1-one (2.4 g) and methanesulfonic acid (40 ml) is heated at 120° C. for 40 minutes. Work-up of the reaction mixture gives the crude product, which is purified by flash chromatography by eluting with methylene chloride-methanol solution. The yield is 0.5 g.

Herkunft & Nachweise