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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1017753Generated: October 31, 2026

HCID 178418361, compound → 5-(2,3-dihydro-1H-inden-1-yl)-1H-imidazole

https://huagongshe.com/reaction/1017753

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178418361HCID 178418361—
ReactantHCID 178419845HCID 178419845—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product5-(2,3-dihydro-1H-inden-1-yl)-1H-imidazoleHCID 178419883—

Reaction Steps

4-(3H-Inden-1-yl)-1H-imidazole hydrochloride (80 mg) is dissolved in ethanol (6 ml). The reaction solution is hydrogenated at 40-50° C. with 10% palladium on carbon as catalyst until no more hydrogen is consumed. Work-up of the reaction mixture gives the crude product which is purified by flash chromatography using methylene chloride-methanol as eluent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479530B2
Source datasetuspto-grants-2002_11
ORD IDord-4e205765707745dd9c4185c1e247a168
Source noteuspto-grants-2002_11