Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | 4-Iodo-3-nitro-benzophenone | HCID 11187302 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Amino-4-iodo-benzophenone | HCID 18404893 | — |
Reaction Steps
A mixture of 5.0 g (14 mmol) of 4-iodo-3-nitro-benzophenone, 7.5 g (42 mmol) of sodium dithionite, 40 ml of pyridine and 15 ml of water is heated to 40° C. for 2 hours. Then the mixture is concentrated in vacuo, combined with ice water and extracted with ethyl acetate. The organic phase is dried with sodium sulphate and the solvent is distilled off in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06479524B1 |
|---|
| Source dataset | uspto-grants-2002_11 |
|---|
| ORD ID | ord-3b9cd23a6a8f4bd8aaf0982c10cd3699 |
|---|
| Source note | uspto-grants-2002_11 |
|---|
