Hydrazine → HCID 18405030, compound

HRID 1017799Notes

Reaction equation

HRID 1017799 reaction equation
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([C:9](=O)[C:10]([CH3:16])([CH3:15])[C:11](OC)=[O:12])=[C:4]([CH3:18])[CH:3]=1.[NH2:19][NH2:20]>O1CCCC1.C(O)C>[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([C:9]2[C:10]([CH3:16])([CH3:15])[C:11](=[O:12])[NH:20][N:19]=2)=[C:4]([CH3:18])[CH:3]=1

Participants

5

Reactant 2

HCID 9321HydrazineHCID 18405136HCID 18405136, compound

Product 1

HCID 18405030HCID 18405030, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

3.5 g (11.7 mmol) of methyl 3-(4-bromo-2,5-dimethyl-phenyl)-2,2-dimethyl-3-oxo-propionate and 28 ml (28 mmol) of 1 molar hydrazine solution in tetrahydrofuran are refluxed in 50 ml of ethanol for 24 hours. The solvent is distilled off and the residue is recrystallised from ethanol.

Workup

  1. distillationThe solvent is distilled off
  2. customthe residue is recrystallised from ethanol

Sources & evidence

ORD record
ord-be6a94fb0ac4453ab6a8c34f74f1dbdc
Source dataset
uspto-grants-2002_11
Patent number
US06479524B1

Reaction notes

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