Chloroform → HCID 18760538, compound

HRID 1017973Notes

Reaction equation

[CH3:1][C:2]([NH2:7])([CH3:6])[CH2:3][NH:4][CH3:5].[CH2:8]([C:10]([CH2:12][CH3:13])=O)[CH3:9].[OH-:14].[Na+].[CH:16](Cl)(Cl)Cl>>[CH3:5][N:4]1[CH2:3][C:2]([CH3:6])([CH3:1])[NH:7][C:10]([CH2:12][CH3:13])([CH2:8][CH3:9])[C:16]1=[O:14]

Participants

Reactant 4

HCID 6212Chloroform

HCID 7288Ethyl ketone

HCID 14798Sodium Hydroxide

HCID 18760539HCID 18760539, compound

Product 1

HCID 18760538HCID 18760538, compound

Procedure

In analogy to Example B21, 1,1-Dimethyl-2-methylaminoethylamin (prepared according M. Senkus, J. Am. Chem. Soc. 68, 10 (1946)), diethylketon, chloroform and NaOH are reacted to give the title compound as a colorless oil.

Sources & evidence

ORD record: ord-ad2b79cddd124f758987f0ad479d238f
Source dataset: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06479608B1

Reaction notes

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