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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1017974Generated: October 26, 2026

Chloroform → 1-t-Butyl-3-isobutyl-3,5,5-trimethyl-piperazin-2-on

https://huagongshe.com/reaction/1017974

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroformHCID 6212—
ReactantMethyl Isobutyl KetoneHCID 7909—
ReactantSodium HydroxideHCID 14798—
Reactant1,2-Propanediamine, N1-(1,1-dimethylethyl)-2-methyl-HCID 12580989—
Product1-t-Butyl-3-isobutyl-3,5,5-trimethyl-piperazin-2-onHCID 18760476—

Reaction Steps

In analogy to Example B21, 1,1-dimethyl-2-t-butylaminoethylamin, methylisobutylketon, chloroform and NaOH are reacted to give the title compound as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479608B1
Source datasetuspto-grants-2002_11
ORD IDord-d4c282c1756f43cd9e95c1549fe2e94a
Source noteuspto-grants-2002_11