Sodium ion → 5-(2-{4-[5-(4-Fluoro-phenyl)-4-methoxymethyl-oxazol-2-yl]-piperidin-1-yl}-ethyl)-2-methoxy-benzenesulfonamide

HRID 101815Notes

Reaction equation

HRID 101815 reaction equation
[CH:39]([N:40]([CH:41]([CH3:42])[CH3:43])[CH2:44][CH3:45])([CH3:46])[CH3:47].[Cl:22][CH2:23][CH2:24][c:25]1[cH:26][cH:27][c:28]([O:35][CH3:36])[c:29]([S:31](=[O:32])(=[O:33])[NH2:34])[cH:30]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:19][O:20][CH3:21])[n:10][c:11]([CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[o:12]2)[cH:6][cH:7]1.[I-:38].[Na+:37].[O:48]1[CH2:49][CH2:50][O:51][CH2:52][CH2:53]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:19][O:20][CH3:21])[n:10][c:11]([CH:13]3[CH2:14][CH2:15][N:16]([CH2:23][CH2:24][c:25]4[cH:26][cH:27][c:28]([O:35][CH3:36])[c:29]([S:31](=[O:32])(=[O:33])[NH2:34])[cH:30]4)[CH2:17][CH2:18]3)[o:12]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 30165Iodide IonHCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 187004064-[5-(4-Fluoro-Phenyl)-4-Methoxymethyl-Oxazol-2-yl]-PiperidineHCID 187004435-(2-Chloroethyl)-2-methoxy-benzenesulfonamide

Product 1

HCID 187004405-(2-{4-[5-(4-Fluoro-phenyl)-4-methoxymethyl-oxazol-2-yl]-piperidin-1-yl}-ethyl)-2-methoxy-benzenesulfonamide

Sources & evidence

ORD record
ord-6231dfd383624cccbcc0727416a2584b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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