Benzoyl Peroxide → HCID 18398678, compound

HRID 1018957Notes

Reaction equation

HRID 1018957 reaction equation
[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[C:11]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[CH:16]=2)[CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].C1C(=O)N([Br:29])C(=O)C1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:29][CH2:21][C:17]1[CH:16]=[C:15]([C:11]2[CH:12]=[CH:13][CH:14]=[C:9]([P:4]([O:3][CH2:1][CH3:2])([O:6][CH2:7][CH3:8])=[O:5])[CH:10]=2)[CH:20]=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 18398694HCID 18398694, compound

Product 1

HCID 18398678HCID 18398678, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

To the compound of Step 2 (0.122 g, 0.400 mmol) in CCl4 (5 mL) were added NBS (0.050 g, 0.480 mle) and a catalytic amount of benzoyl peroxide. The reaction mixture was refluxed under light for 2 h. The reaction was cooled to room temperature, filtered and evaporated. The title compound was obtained after purification by flash chromatography. (0.150 g).

Workup

  1. temperatureThe reaction mixture was refluxed under light for 2 h
  2. filtrationfiltered
  3. customevaporated

Sources & evidence

ORD record
ord-557cd8f77fc643b5afa8c887916d1cd5
Source dataset
uspto-grants-2002_11
Patent number
US06486141B2

Reaction notes

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