HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 4-[(E)-3-(imidazol-5-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate → 4-[(E)-3-(imidazol-5-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 4-[(E)-3-(imidazol-5-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate | HCID 18399501 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-[(E)-3-(imidazol-5-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoic acid | HCID 18399508 | — |
Reaction Steps
A solution of methyl 4-[(E)-3-(imidazol-5-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate (0.6 g; 1.8 mmol) in 1N HCl (15 ml) was refluxed for 20 hours. The mixture was evaporated to dryness to give 4-[(E)-3-(imidazol-5-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoic acid as the hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06486156B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-0d710f8830004c74bacf13d0f85dc502 |
| Source note | uspto-grants-2002_11 |