Methyl iodide → HCID 18398717, compound

Participants

Reaction Steps

To a suspension of 2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one (0.5 g, 2.3 mmol) in acetone (10 mL) at r.t. was added MeI (0.17 mL, 2.7 mmol), followed by K2CO3 (315 mg, 2.3 mmol). After stirring ON at r.t., the solvent was removed and the residue was taken up in Et2O/H2O. The organic layer was dried (MgSO4), filtered, and evaporated to yield o.43 g of the title compound.

Provenance & Evidence