m-Chloroperbenzoic acid → HCID 18399125, compound

Participants

Reaction Steps

To a solution of the compound obtained in Example 121 (200 mg) in chloroform (15 ml) is added a solution of m-chloroperbenzoic acid (78 mg) in chloroform (10 ml) at room temperature, and the mixture is stirred for one hour. The reaction mixture is washed with a 5% aqueous sodium hydroxide solution, dried, and concentrated under reduced pressure to give 6,7-dimethoxy-3-methoxycarbonyl-2-(3-methylsulfinylphenyl)-4-(3,4,5-trimethoxyphenyl)-1(2H)-isoquinolinone (1750 mg) as listed in Table 11.

Provenance & Evidence