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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019545Generated: October 30, 2026

Pyrrolidine → HCID 66907417, compound

https://huagongshe.com/reaction/1019545

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantN-[6-Chloropyridin-3-yl]-6-trifluoromethyl-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 86639060—
ProductHCID 66907417HCID 6690741764.8%

Reaction Steps

According to a method similar to that described in Stage 6.2, by reacting 0.3 g (0.67 mmol) of N-[6-chloropyridin-3-yl]-6-trifluoromethyl-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide, described in the preceding stage, with 0.56 mL (6.68 mmol) of pyrrolidine, we obtain 0.21 g of the expected compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716272B2
Source datasetuspto-grants-2014_05
ORD IDord-2f7d8f1d1b2e4e69ac7198e16489ac26
Source noteuspto-grants-2014_05