反应详情

The product of Example 1, step (d) (80 mg, 0.35 mmol) was dissolved in 2 mL of 1:1 CHCl3:HOAc and treated with NBS (62 mg, 0.35 mmol). After 15 minutes, the reaction was concentrated to dryness, dissolved in a minimal amount of EtOAc and filtered through a pad of silica gel. The filtrate was evaporated to give 105 mg of the sub-title compound.

1. concentrationthe reaction was concentrated to dryness
2. dissolutiondissolved in a minimal amount of EtOAc
3. filtrationfiltered through a pad of silica gel
4. customThe filtrate was evaporated