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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019832Generated: October 31, 2026

5-(Boc-amino)-1-pentanol → tert-Butyl 5-(4-chloro-5-fluoro-2-(hydroxymethyl)phenoxy)pentylcarbamate

https://huagongshe.com/reaction/1019832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Boc-amino)-1-pentanolHCID 4456136—
ReactantMethyl 5-chloro-4-fluoro-2-hydroxybenzoateHCID 67449737—
Producttert-Butyl 5-(4-chloro-5-fluoro-2-(hydroxymethyl)phenoxy)pentylcarbamateHCID 68229609—

Reaction Steps

Intermediate I-30 was prepared from methyl 5-chloro-4-fluoro-2-hydroxybenzoate and tert-butyl 5-hydroxypentylcarbamate analogously to Examples 27-28.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716293B2
Source datasetuspto-grants-2014_05
ORD IDord-3814e105d7234f539558d33a2ba852c8
Source noteuspto-grants-2014_05