Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019833Generated: October 30, 2026

Benzoic acid, 5-chloro-2-hydroxy-, methyl ester → tert-Butyl 5-(4-chloro-2-(hydroxymethyl)phenoxy)pentylcarbamate

https://huagongshe.com/reaction/1019833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic acid, 5-chloro-2-hydroxy-, methyl esterHCID 77684—
Reactant5-(Boc-amino)-1-pentanolHCID 4456136—
Producttert-Butyl 5-(4-chloro-2-(hydroxymethyl)phenoxy)pentylcarbamateHCID 68229693—

Reaction Steps

Intermediate I-31 was prepared from methyl 5-chloro-2-hydroxybenzoate and tert-butyl 5-hydroxypentylcarbamate analogously to Examples 24-26.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716293B2
Source datasetuspto-grants-2014_05
ORD IDord-c327f163f30d4b3fa120a91a9cb8abd3
Source noteuspto-grants-2014_05