HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Cyanide → HCID 71699857, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 4-chloro-N-methylbutane-1-sulfonamide | HCID 10375164 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 71699857 | HCID 71699857 | — |
Reaction Steps
4-Chloro-N-methylbutane-1-sulfonamide (54 mmol), KCN (108 mmol) and 18-crown ether-6 (11 mmol) were dissolved in CH3CN (100 ml). The mixture was stirred at reflux temperature overnight. The mixture was cooled and filtered. The residue was purified by flash column chromatography over silica gel (eluent: CH2Cl2, then ethyl acetate). Yield: 3.2 g (70% purity).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716293B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-65ee3938be8f4713a3559e2edf75039d |
| Source note | uspto-grants-2014_05 |