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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019870Generated: October 27, 2026

3-Bromo-1-propanol → C-{1-[3-(7-methoxy-quinoxalin-2-yloxy)-propyl]-piperidin-4-yl}-methylamine

https://huagongshe.com/reaction/1019870

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-1-propanolHCID 12308—
ReactantTert-butyl (piperidin-4-ylmethyl)carbamateHCID 723429—
Reactant2-Chloro-7-methoxyquinoxalineHCID 12686415—
ProductC-{1-[3-(7-methoxy-quinoxalin-2-yloxy)-propyl]-piperidin-4-yl}-methylamineHCID 66746562—

Reaction Steps

The title compound is prepared as a brown viscous oil following Scheme 1 and in analogy to Example 1 using 2-chloro-7-methoxy-quinoxaline, 3-bromo-propan-1-ol and piperidin-4-ylmethyl-carbamic acid tert-butyl ester as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716280B2
Source datasetuspto-grants-2014_05
ORD IDord-e5306eb2050442c7a3928a21ea6d2237
Source noteuspto-grants-2014_05